Central German Mental Health Center

The CMC houses a large array of infrastructural and research tools, both for basic neuroscience and disease- and patient-oriented research. Examplary components are summarized in the following table.

INFRASTRUCTURE SPECIFICATION
3 T Human MRI Core Facility, MR 3-Tesla MR-scanner (Siemens Trio) dedicated for research. Access to MR-compatible EEG systems, various MR-compatible eye-trackers, movement and psychophysiological systems
3 T Human MRI Core Facility, GI 3-Tesla MR-scanner (Siemens Prisma) dedicated for research. Access to MR-compatible EEG systems, various MR-compatible eye-trackers, movement and psychophysiological systems
Molecular Imaging Facility Access to SPECT-PET-CT, offering expertise to study functional and morphologic parameters
7T-small animal MRI 7-Tesla MR-scanner for investigation of experimental animals with a weight of up to 1.2 kg
Comprehensive Biomaterial Bank Marburg (CBBMR) Scientific service platform constituting a department-wide, central collection of biomaterials in a modular way (Member of German Biobank Alliance/GBA)
Genomics Core Facility
(including Single Cell Sequencing & Multiomics)
Infrastructure for various genome-wide analysis techniques, offering access to several instrument- and cost-intensive technologies of modern biomedicine (e.g. next generation sequencers, Rhapsody Single Cell Multiomics system)
Cellular Imaging – Spinning Disc Confocal Microscopy Access to Spinning disc microscopy, representing one of the most powerful imaging techniques to analyze the biological dynamics of living cells
Multiphoton Microscopy Multiphoton microscopy, combining the advanced optical techniques of laser scanning microscopy with long wavelength multiphoton fluorescence excitation for imaging of cells deep in living (brain) tissue
Laser Microdissection Laser Microdissection, allowing for the contact- and contamination-free isolation of single cells or entire areas of tissue
Medicinal Chemistry Unit The Medicinal Chemistry unit supports the design, synthesis and structural optimization of small organic compounds that can be used as research tools
Bioimaging Facility Access to different state-of-the-art microscopes (e.g. widefield fluorescence and confocal microscopes, electron microscope, Total Internal Reflection Fluorescence microscope)
hessian.AI 10 NVIDIA DGX2/A100 AI Supercomputers and corresponding data storage as part of the recently started Hessian Center for AI (hessian.AI) with personnel for all aspects of cognitive modelling and big data analyses
MaRC3 High-performance computing cluster
Coordinating Center for Clinical Studies (KKS) Large University-based KKS, offering GCP-compliant implementation of Investigator Initiated Studies (IITs). study management, study protocols, contracts, legal work, analysis and publication of clinical studies
TransMit GmbH University based transfer unit assisting in founding start up companies and in patient mining, filing an intellectual property protection
Data Hub Data platform. Storage, mining, and interface structure for making data Findable, Accessible, Interoperable and Reusable (FAIR) to the scientific community
CMBB A joint research center of the Universities of Marburg and Gießen. Researchers of various neuroscientific disciplines are collaborating interdisciplinary
Research Campus of Central Hessen (FCMH) Recently established platform to further promote the research infrastructure of the three Central Hessian universities. A central focus of the research campus is the topic Mind, Brain and Behavior
Psychiatric Imaging Network Germany (PING) The DZP is part of this neuroimaging network. It serves to coordinate, standardize and optimize data acquisition and storage of neuroimaging studies.
Virtual reality and movement tracking lab To study human behavior in 3D environments (one in MR, one in GI), specialized among others for eye-tracking investigation of infants
Deep Brain Stimulation DBS in PD patients and iEEG in pharmaco-resistant epileptic patients
Rodent Behavior Facility A self-contained S1 in-house animal facility for N=720 rats in Marburg and for N=100 rats and N=100 mice in Giessen with behavioral test rooms fully equipped for assessing behavioral phenotypes with relevance to human neuropsychiatric disorders
Psychophysiology Facilities Psychophysiological labs with continuous blood pressure measurement, heart rate and baroreflex sensitivity, respiration, surface EMG, ECG and SCL to measure the influence of stress on chronic disorders and diseases
Virtual Reality Treatment Centers Network (VRNet) vR-treatment with programs to develop a higher perception of physical introspection to influence stress symptoms and chronic diseases
IDeA Labs Joint lab structure of DIPF, JWG and Sigmund-Freud-Institute comprising equipment for behavioral and neurocognitive studies inside and outside the labs (paper-based tests, computer-assisted cognitive tests, video studies): 4 eye-trackers (1 mobile device), 1 EEG system, 1 MRT training device, testing library (with more than 450 items)
Behavioral Neuroscience Lab Eye tracking, functional near-infrared
spectroscopy (fNIRS), EEG Speech and Motion capture
Brain stimulation & EEG lab MR tDCS, TMS, EEG and experimental equipment
AP MALDI MS Imaging High-resolution atmospheric-pressurescanning microprobe matrix-assisted laser desorption/ionization orbital trapping mass spectrometry imaging
Noninvasive Brain Stimulation Multi-channel tDCS, tACS and 3D current flow modelling for focused stimulation
EEG lab 64-channel EEG and experimental software, source space and connectivity analysis
Virtual Reality Treatment lab Free movements social situation training facility