Central German Mental Health Center

Selected publications of the CMC Faculty Representatives.

  • Antilla V, …, Nenadic I, … Murray R (2018) Analysis of shared heritability in common disorders of the brain. Science 360: eaap8757.
    DOI: 10.1126/science.aap8757
  • Bohus M, …, Steil R.,…  Priebe K (2020) Dialectical Behavior Therapy for Posttraumatic Stress Disorder (DBT-PTSD) Compared With Cognitive Processing Therapy (CPT) in Complex Presentations of PTSD in Women Survivors of Childhood Abuse: A Randomized Clinical Trial. JAMA Psychiatry.
    DOI: 10.1001/jamapsychiatry.2020.2148
  • Bohus M, …, Steil R (2013) Dialectical behaviour therapy for post-traumatic stress disorder after childhood sexual abuse in patients with and without borderline personality disorder: a randomised controlled trial. Psychotherapy and Psychosomatics 82(4): 221–233.
    DOI: 10.1159/000348451
  • Bremmer F, Churan J, Lappe M (2017) Heading representations in primates are compressed by saccades. Nat Commun 8:920.
    DOI: 10.1038/s41467-017-01021-5
  • Chini M, …, Mulert C, Hanganu-Opatz IL (2020) Resolving and Rescuing Developmental Miswiring in a Mouse Model of Cognitive Impairment. Neuron 105:60–74 e67.
    DOI: 10.1016/j.neuron.2019.09.042
  • Curcic-Blake B, …, Mulert C, …, Aleman A (2017) Interaction of language, auditory and memory brain networks in auditory verbal hallucinations. Prog Neurobiol 148: 1–20.
    DOI: 10.1016/j.pneurobio.2016.11.002
  • Deuschl G, …, Timmermann L, ..., Voges J (2006) Deep brain stimulation for Parkinson’s disease – a 6-month randomized, controlled trial. N Engl J Med 355 (9): 896–908.
    DOI: 10.1056/NEJMoa060281
  • Emeny RT, …,Kruse J, Ladwig KH (2018) Anxiety associated increased CpG methylation in the promoter of Asb1: A translational approach evidenced by epidemiological and clinical studies and a murine model. Biol Psychiat 43(2): 342–353.
    DOI: 10.1038/npp.2017.102
  • Enck P, Bingel U, Schedlowski M, Rief W (2013) Minimize, maximize, or personalize? – What to do with the placebo response in medicine? Nat Rev Drug Discov 12:191–204.
    DOI: 10.1038/nrd3923
  • Forstner AJ, … , Kircher T, Pané-Farré CA, Pauli P, Rief W, …, Becker J (2019) Genome-wide association study of panic disorder reveals genetic overlap with neuroticism and depression. Mol Psychiatry, Advance online publication.
    DOI: 10.1038/s41380-019-0590-2
  • Grossheinrich N, …, Mulert C, …, Padberg F (2009) Theta burst stimulation of the prefrontal cortex: safety and impact on cognition, mood, and resting electroencephalogram. Biol Psychiatry 65: 778–784.
    DOI: 10.1016/j.biopsych.2008.10.029
  • de Haas B, Iakovidis AL, Schwarzkopf S, Gegenfurtner KR (2019) Individual differences in visual salience vary along semantic dimensions. Proceedings of the National Academy of Sciences USA 116(24): 11687–11692.
    DOI: 10.1073/pnas.1820553116
  • Hahn T, Kircher T, Straube B, …, Lueken U (2015) Predicting treatment response to cognitive behavioral therapy in panic disorder with agoraphobia by integrating local neural information. JAMA Psychiatry 72:68–74.
    DOI: 10.1001/jamapsychiatry.2014.1741
  • Hansen K, …, Steil R (2013). Efficacy of psychological interventions aiming to reduce chronic nightmares: A meta-analysis. Clinical Psychology Review 33(1): 146–155.
    DOI: 10.1016/j.cpr.2012.10.012
  • Hansen T, Olkkonen M, Walter S, Gegenfurtner KR (2006) Memory modulates color appearance. Nature Neuroscience 9: 1367–1368.
    DOI: 10.1038/nn1794
  • Jung K, Steil R (2013) A randomized controlled trial on cognitive restructuring and imagery modification to reduce the feeling of being contaminated in adult survivors of childhood sexual abuse suffering from PTSD. Psychotherapy and Psychosomatics 82(4): 213–220.
    DOI: 10.1159/000348450
  • Kamitaki N, …, Nenadic I, …, McCarroll S (2020) Complement genes contribute sex-biased vulnerability in diverse disorders. Nature 582:577–581.
    DOI: 10.1038/s41586-020-2277-x
  • Huys D, …, Timmermann L, …, Kuhn J (2016) Motor improvement and emotional stabilization in patients with Tourette syndrome after deep brain stimulation of the ventral anterior and ventrolateral motor part of the thalamus. Biol Psychiatry 79(5):392–401.
    DOI: 10.1016/j.biopsych.2014.05.014
  • Kircher T, …, Straube B (2013) Effect of Cognitive-Behavioral Therapy on Neural Correlates of Fear Conditioning in Panic Disorder. Biol Psychiatry 73:93–101.
    DOI: 10.1016/j.biopsych.2012.07.026
  • Kircher T, Bröhl H, Meier F, Engelen J (2018) Formal thought disorders: from phenomenology to neurobiology. Lancet Psychiatry 5:515–526.
    DOI: 10.1016/S2215-0366(18)30059-2
  • Kleinstäuber M, …, Stark, R,…, Rief W (2019) Cognitive behaviour therapy complemented with emotion regulation training for patients with persistent physical symptoms: A randomised clinical trial. Psychotherapy and Psychosomatics 88: 287–299.
    DOI: 10.1159/000501621
  • Krekelberg B, …, Bremmer F, Ross J (2003) Neural correlates of implied motion. Nature 424:674–677.
    DOI: 10.1038/nature01852
  • Krekelberg B, Kubischik M, Hoffmann K-P, Bremmer F (2003) Neural correlates of visual localization and perisaccadic mislocalization. Neuron 37:537–545.
    DOI: 10.1016/s0896-6273(03)00003-5
  • Kruse J, …, Thefeld W (2003) On the association between diabetes and mental disorders in a community sample. Diabetes Care 26: 1841–1846.
    DOI: 10.2337/diacare.26.6.1841
  • Kube T, …, & Rief W (2020) Distorted Cognitive Processes in Major Depression: A Predictive Processing Perspective. Biol Psychiatry 87(5):388–398.
    DOI: 10.1016/j.biopsych.2019.07.017
  • Leichsenring F, Leweke F (2017) Social anxiety disorder. New England Journal of Medicine 376:  2255–2264.
    DOI: 10.1056/NEJMcp1614701
  • Leichsenring F, Rabung S (2008) Effectiveness of long-term psychodynamic psychotherapy: a meta-analysis. JAMA 300: 1551–1565.
    DOI: 10.1001/jama.300.13.1551
  • Leichsenring F, Sarrar L, Steinert C (2019) Drop-outs in psychotherapy: a change of perspective. World Psychiatry 18: 32–33.
    DOI: 10.1002/wps.20588
  • Leichsenring F, ..., Steinert C (2015) Psychodynamic Therapy Meets Evidence-Based Medicine: A Systematic Review Using Updated Criteria. Lancet Psychiatry 2: 648–660.
    DOI: 10.1016/S2215-0366(15)00155-8
  • Leichsenring F, Leibing E, Kruse J, Leweke F (2011) Borderline personality disorder. Lancet 377: 74–84.
    DOI: 10.1016/S0140-6736(10)61422-5
  • Leicht G*, Mulert C*, …, Rupprecht R (2013) Benzodiazepines counteract rostral anterior cingulate cortex activation induced by cholecystokinin-tetrapeptide in humans. Biol Psychiatry 73: 337–344. * contributed equally
    DOI: 10.1016/j.biopsych.2012.09.004
  • Leicht G, …, Mulert C (2010) Reduced early auditory evoked gamma-band response in patients with schizophrenia. Biol Psychiatry 67: 224–231.
    DOI: 10.1016/j.biopsych.2009.07.033
  • Lueken U, Straube B, …, Jansen A, …, Kircher T (2013) Neural Substrates of Treatment Response to Cognitive-Behavioral Therapy in Panic Disorder With Agoraphobia. Am J Psychiatry 170:1345–1355.
    DOI: 10.1176/appi.ajp.2013.12111484
  • Petrie KJ, Rief W (2019) Psychobiological mechanisms of placebo and nocebo effects: Pathways to improve treatments and reduce side effects. Ann Rev Psychol 70:12.1–12.27.
    DOI: 10.1146/annurev-psych-010418-102907
  • Rief W, …, . Wambach K (2018) Comparing the efficacy of CBASP with two versions of CBT for depression in a routine care center: A randomized clinical trial. Psychother Psychosom 87:164–178.
    DOI: 10.1159/000487893
  • Rief W, Martin A (2014) How to use the new DSM-5 diagnosis Somatic Symptom Disorder in research and practice? – A critical evaluation and a proposal for modifications. Ann Rev Clinical Psychol 10:339–67.
    DOI: 10.1146/annurev-clinpsy-032813-153745
  • Risch AK, Taeger  S, Brüdern J, Stangier U (2013) Psychological Well-Being in Remitted Patients with Recurrent Depression. Psychotherapy and Psychosomatics, 83: 404–405.
    DOI: 10.1159/000351808
  • Rosner R, …, Steil R (2019) Effect of developmentally adapted cognitive processing therapy for youth with symptoms of posttraumatic stress disorder after childhood sexual and physical abuse: A randomized clinical trial. JAMA Psychiatry 76(5): 484–491.
    DOI: 10.1001/jamapsychiatry.2018.4349
  • Ruderfer DM, …, Nenadic I, …, Kendler KS (2018) Genomic dissection of bipolar disorder and schizophrenia, including 28 subphenotypes. Cell 173(7):1705–1715.
    DOI: 10.1016/j.cell.2018.05.046
  • Sack M, Kruse J, Stingl M (2016) A comparison of dual attention, eye movements, and exposure only during eye movement desensitization and reprocessing for posttraumatic stress disorder: Results from a randomized clinical trial. Psychother Psychosom 85(6):
    DOI: 10.1159/000447671
  • Schramowski W,…, Kersting K (2020) Making deep neural networks right for the right scientific reasons by interacting with their explanations. Nature Machine Intelligence 2:476–486.
  • Schuepbach WM, …, Timmermann L, …, Deuschl G; EARLYSTIM Study Group (2013) Neurostimulation for Parkinsons disease with early motor complications. N Engl J Med 368(7):610–22.
    DOI: 10.1056/NEJMoa1205158
  • Schütz A C, Braun, DI, Kerzel D, Gegenfurtner KR (2008) Improved visual sensitivity during smooth pursuit eye movements: Nature Neuroscience 11: 1211–1216.
    DOI: 10.1038/nn.2194
  • Stangier U, … Clark, D.M. (2011). Cognitive Therapy versus Interpersonal Psychotherapy in Social Phobia: A randomized controlled trial. Archives of General Psychiatry, 68, 692–700.
    DOI: 10.1001/archgenpsychiatry.2011.67
  • Stangier U, …, Hautzinger M (2013) Maintenance cognitive-behavioral therapy and manualized psychoeducation in the treatment of recurrent depression: a multicenter prospective randomized controlled trial. American Journal of Psychiatry 170: 624–632.
    DOI: 10.1176/appi.ajp.2013.12060734
  • Steinert C, …, Leichsenring F,…, Kruse J (2016) Treating post-traumatic stress disorder by resource activation in Cambodia. World Psychiatry 15(2): 183–185.
    DOI: 10.1002/wps.20303
  • Straube B, …, Jansen A, …, Kircher T (2014) Neural correlates of procedural variants in cognitive behavioral therapy: A randomized, controlled multicentre fMRI study. Psychotherapy and Psychosomatics 83:222–233.
    DOI: 10.1159/000359955
  • Timmermann L, ..., Leenders KL (2010) Dystonia in neurodegeneration with brain iron accumulation: outcome of bilateral pallidal stimulation. Brain 133(3): 701–712.
    DOI: 10.1093/brain/awq022
  • Timmermann L, …, Alesch F (2015) Multiple source current steering in subthalamic nucleus deep brain stimulation for Parkinson’s disease: the multi-center, prospective VANTAGE trial. Lancet Neurol 14(7):693–701.
    DOI: 10.1016/S1474-4422(15)00087-3
  • Valluy J, …, Wöhr M, …, Schratt G (2015) A coding-independent function of an alternative Ube3a transcript during neuronal development. Nat Neurosci 18:666–673.
    DOI: 10.1038/nn.3996
  • van Velzen LS, Kelly S, …, Kircher T, …, Schmaal L (2020) White matter disturbances in major depressive disorder: a coordinated analysis across 20 international cohorts in the ENIGMA MDD working group. Mol Psychiatry 25:1511–1525.
    DOI: 10.1038/s41380-019-0477-2
  • Weber H, …, Straube B, … Pané-Farré C, … Kircher T, …, Scholz CJ (2016) Allelic variation in CRHR1 predisposes to panic disorder: evidence for biased fear processing. Mol Psychiatry 21:813–822.
    DOI: 10.1038/mp.2015.125
  • Wendt J, …, Pané-Farré CA, …, Kircher T, …, Richter J (2018) Pre-treatment cardiac vagal tone predicts dropout from and residual symptoms after exposure therapy in patients with panic disorder and agoraphobia. Psychother Psychosom 87:187–189.
    DOI: 10.1159/000487599
  • Wittmann A, …, Straube B, …, Kircher T, Ströhle A (2018) Effects of cognitive behavioral therapy on neural processing of agoraphobia-specific stimuli in panic disorder and agoraphobia. Psychotherapy and Psychosomatics 87:350–365.
    DOI: 10.1159/000493146
  • Yang Y, …, Straube B, Kircher T (2020) Effect of CBT on Biased Semantic Network in Panic Disorder: A Multicenter fMRI Study Using Semantic Priming. Am J Psychiatry 177:254–264.
    DOI: 10.1176/appi.ajp.2019.19020202